CDK15/CycB1 Kinase Activity Assay Service

Activity-based CDK15/CycB1 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

CDK15/CycB1

Enzyme

Human CDK15/CycB1, wt

HGNC

CDK15-CCNB1

Manning ID

PFTAIRE2

Synonym

PFTAIRE2, ALS2CR7, PFTK2

UniProt

Q96Q40 (CDK15_HUMAN)

Kinase Type

Protein kinase

Kinase Group

CMGC

Assay Properties

Assay Format

33PanQinaseTM

Substrates

RBER-NTRK3tide, ATP

Reaction

RBER-NTRK3tide + 33P-ATP = 33P-RBER-NTRK3tide + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 19
Sorafenib 71000
Sunitinb 71000

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice CDK15/CycB1
345 wt Profiler No
345 IC50 wt Profiler No
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

Yes; ProQinaseTM – CDK15/CycB1
(Activity verified by 33PanQinaseTM-Assay)

Product Number

1889-0135-1

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