CDK16/cyclin Y Kinase Assay Service

Activity-based CDK16/cyclin Y kinase assay for compound screening and profiling via radiometric HotSpot^TM kinase assay.

Target Overview

CAT#

CDK16/Cyclin Y

Enzyme

Human CDK16/Cyclin Y

HGNC

CDK16/CCNY

Synonym

PCTAIRE1, PCTAIRE, PCTGAIRE, PCTK1

Substrates

RB protein, 3 µM
ATP 10 µM

Assay Properties

Reaction

Substrate + [γ-³³P]-ATP = ³³P-Substrate + ADP

Readout

Enzymatic activity

Reference Compound IC50s

Scientific Information

CDK16: Q00536 (http://www.uniprot.org/uniprot/Q00536)Cyclin Y: Q8ND76 (http://www.uniprot.org/uniprot/Q8ND76)

Screening Location

Malvern, USA

Reference compound IC50 for CDK16/Cyclin Y