CDK17/cyclin Y Kinase Assay Service

Activity-based CDK17/cyclin Y kinase assay for compound screening and profiling via radiometric HotSpot^TM kinase assay.

Target Overview

CAT#

CDK17/Cyclin Y

Enzyme

Human CDK17/Cyclin Y

HGNC

CDK17/CCNY

Synonym

PCTAIRE2, PCTK2

Substrates

MBP (Myelin Basic Protein), 20 µM
ATP 10 µM

Assay Properties

Reaction

Substrate + [γ-³³P]-ATP = ³³P-Substrate + ADP

Readout

Enzymatic activity

Reference Compound IC50s

Scientific Information

CDK17: Q00537 (http://www.uniprot.org/uniprot/Q00537)Cyclin Y: Q8ND76 (http://www.uniprot.org/uniprot/Q8ND76)

Screening Location

Malvern, USA

Reference compound IC50 for CDK17/Cyclin Y (PCTK2)