CDK19/cyclin C Kinase Assay Service

Activity-based CDK19/cyclin C kinase assay for compound screening and profiling via radiometric HotSpot^TM kinase assay.

Target Overview

CAT#

CDK19/Cyclin C

Enzyme

Human CDK19/Cyclin C

HGNC

CDK19/CCNC

Synonym

CDC2L6, CDK11

Substrates

Protein substrate, Pol2-CTD, 5 µM
ATP 10 µM

Assay Properties

Reaction

Substrate + [γ-³³P]-ATP = ³³P-Substrate + ADP

Readout

Enzymatic activity

Reference Compound IC50s

Scientific Information

CDK19: Q9BWU1 (http://www.uniprot.org/uniprot/Q9BWU1)
Cyclin C: P24863 (http://www.uniprot.org/uniprot/P24863)

Screening Location

Malvern, USA

Further information

More information can be found on our website Kinase Assays.

Reference compound IC50 for CDK19/cyclin C