CDK3/CycC Kinase Activity Assay Service

Activity-based CDK3/CycC kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview
RBE Target ID

CDK3/CycC

Enzyme

Human CDK3/CycC, wt

HGNC

CDK3-CCNC

Manning ID

CDK3

Synonym

CDKN3, CDK3, CDK3/CycC

UniProt

Q00526 (CDK3_HUMAN)

Kinase Type

Protein kinase

Kinase Group

CMGC

Assay Properties
Assay Format

33PanQinaseTM

Substrates

RBER-CHKtide, ATP

Reaction

RBER-CHKtide + 33P-ATP = 33P-RBER-CHKtide + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 17
Sorafenib 10000
Sunitinib 16000
Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability
Screening Opportunities
FreeChoice CDK3/CycC
355 wt Profiler Yes
355 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler IC50 CDK Profiler
Recombinant Protein Availability
Active recombinant protein Yes; ProQinaseTM – CDK3/CycC
(Activity verified by 33PanQinaseTM-Assay)
Product Number 0212-0390-1
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