Activity-based CDK3/CycO kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology
Target Overview
RBE Target ID
CDK3/CycO
Enzyme
Human CDK3, wt
HGNC
CDK3
Manning ID
CDK3
Synonym
CDK3, CDKN3
UniProt
Kinase Type
Protein kinase
Kinase Group
CMGC
Assay Properties
Assay Format
33PanQinaseTM
Substrates
RBER-CHKtide, ATP
Reaction
Substrate + 33P-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Technical Reference Compound IC50 value(s)
| Compounds | IC50 (nM) |
|---|---|
| Staurosporine | 10 |
| Sorafenib | >100000 |
| Sunitinib | 20000 |
Screening Location
Freiburg, Germany
Further Information
More information can be found on our website Kinase Assays
Service and Product Availability
Screening Opportunities
| FreeChoice | CDK3/CycO |
| wt Profiler Panel | Yes |
| IC50 wt Profiler Panel | Yes |
| Mutant Profiler Addon | No |
| Lipid Kinase Profiler Addon | No |
| IC50 Profiler | No |
Recombinant Protein Availability
| Active recombinant protein | Yes; ProQinaseTM – CDK3/CycO (Activity verified by 33PanQinaseTM-Assay) |
| Product Number | 0212-2135-1 |
| Web Shop | Reaction Biology Online Shop |
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