CECR2 Bromodomain Assay Service (ThermoShift)

CECR2-GST Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.

Target Overview




Human CECR2 bromodomain, GST-tagged


Cat eye syndrome critical region protein 2; KIAA1740

Assay Properties


Thermal stability change after ligand binding

Concentration of protein in assay

0.1 mg/ml (2.46 µM)

Concentration of compound in assay

25 µM

Apo form Tm (°C)


Reference Compound ΔTms:

Bromosporine – 2 (Blue)No stabilization was observed in the presence of other control compounds (JQ1, PFI1, CBP112, SGC-CBP30, BET151, GSK2801 and PFI3)

Scientific Information

Q9BXF3 (http://www.uniprot.org/uniprot/Q9BXF3)

Screening Location

Malvern, USA

Further information

More information can be found on our website Reader Domain Assay Services.

Melt Curve

Melt Curve

Melt Peak

Melt Peak