cIAP-1 Apoptosis Assay Service

cIAP-1 Apoptosis Assay for compound screening and profiling using fluorescence polarization to measure compound binding to the target.
Target Overview

CAT#
cIAP-1

Enzyme
Human cIAP-1 BIR3 domain

Synonyms
Baculoviral IAP repeat-containing protein 2, Cellular inhibitor of apoptosis 1, RING-type E3 ubiquitin transferase BIRC2, IAP homolog B, BIRC2

Substrates
Fluorescence-labeled Probe, 5 nM

Assay Properties

Reaction
Competition binding assay with probe in FP assay.

Reference Compound IC50s
Scientific Information
Q13490 (http://www.uniprot.org/uniprot/Q13490)

Screening Location
Malvern, USA

Probe displacement IC50 for cIAP-1