cIAP-2 Apoptosis Assay Service

cIAP-2 Apoptosis Assay for compound screening and profiling using fluorescence polarization to measure compound binding to the target.
Target Overview
CAT#
cIAP-2
Enzyme
Human cIAP-2 BIR3 domain
Synonyms
Baculoviral IAP repeat-containing protein 3, Cellular inhibitor of apoptosis 2, RING-type E3 ubiquitin transferase BIRC3, IAP homolog C, BIRC3
Substrates
Fluorescence-labeled Probe, 5 nM
Assay Properties
Reaction
Competition binding assay with probe in FP assay.
Reference Compound IC50s
CompoundsIC50 (nM)
Birinapant90
Scientific Information
Q13489 (http://www.uniprot.org/uniprot/Q13489)
Screening Location
Malvern, USA
Probe displacement IC50 for cIAP-2
Probe displacement IC50 for cIAP-2