CK1alpha1 Kinase Activity Assay Service

Activity-based CK1alpha1 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

CK1alpha1

Enzyme

Human CK1alpha1, wt

HGNC

CSNK1A1

Manning ID

CK1a

Synonym

CK1-alpha1, CK1, HLCDGP1, PRO2975, CSNK1A1, CK1alpha1, CK1a1

UniProt

P48729 (KC1A_HUMAN)

Kinase Type

Protein kinase

Kinase Group

CK1

Assay Properties

Assay Format

33PanQinaseTM

Substrates

Casein, ATP

Reaction

Casein + 33P-ATP = 33P-Casein + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Sorafenib 10000
Sunitinb 2600

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice CK1alpha1
345 wt Profiler Yes
345 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

Yes; ProQinaseTM – CK1alpha1
(Activity verified by 33PanQinaseTM-Assay)

Product Number 0406-0000-1
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