CREBBP-GST Reader Domain Assay for compound screening and profiling using the thermoshift assay format to measure compound binding to the target.
Human CREBBP bromodomain, GST-tagged
CREB-binding protein, CBP
Thermal stability change after ligand binding
0.1 mg/ml (2.44 µM)
CBP112 - 8.5 (Blue)SGC-CBP30 - 9.5 (Red)No stabilization was observed in the presence of other control compounds (JQ1, RVX-208, GSK2801 and PFI3)
More information can be found on our website Reader Domain Assay Services.