CSK Kinase Assay Service

Activity-based CSK kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
CSK
Enzyme
Human CSK
HGNC
CSK
Synonym
CSK
Substrates
Peptide substrate, poly[Glu:Tyr] (4:1), 0.2 mg/ml
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Staurosporine14.6
PP2142
AG14783,200
D-644069,500
Scientific Information
P41240 (http://www.uniprot.org/uniprot/P41240)
Screening Location
Malvern, USA
Reference compound IC50 for CSK
Reference compound IC50 for CSK