CTK/MATK Kinase Assay Service

Activity-based CTK/MATK kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
CTK
Enzyme
Human CTK
HGNC
MATK
Synonym
CHK, CTK, DKFZp434N1212, HHYLTK, HYL, Lsk, MGC1708, MGC2101
Substrates
Peptide substrate, poly[Glu:Tyr] (4:1), 0.2 mg/ml
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Staurosporine770
Scientific Information
P42679 (http://www.uniprot.org/uniprot/P42679)
Screening Location
Malvern, USA
Reference compound IC50 for CTK/MATK/HYL
Reference compound IC50 for CTK/MATK/HYL