CYP2D6 for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Cyp2D6 + NADPH-P450 Reductase (microsomes from insect cells that were infected with baculovirus containing the human Cyp2D6 cDNA and rabbit Cytochrome P450 cDNA)
Cytochrome P450, family 2, subfamily D, polypeptide 6
RH + O₂ + NADPH + H⁺ = ROH + H₂O + NADP⁺
More information can be found on our website Cytochrome P450 Assay Services.
Reference compound IC50 for Cyp2D6