DAPK1 Kinase Activity Assay Service

Activity-based DAPK1 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

DAPK1

Enzyme

Human DAPK1, wt

HGNC

DAPK1

Manning ID

DAPK1

Synonym

DAPK1

UniProt

P53355 (DAPK1_HUMAN)

Kinase Type

Protein kinase

Kinase Group

CAMK

Assay Properties

Assay Format

33PanQinaseTM

Substrates

RBER-GSK3(14-27), ATP

Reaction

RBER-GSK3(14-27) + 33P-ATP = 33P-RBER-GSK3(14-27) + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 14
Sorafenib 10000
Sunitinb 1000

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice DAPK1
345 wt Profiler Yes
345 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

Yes; ProQinaseTM – DAPK1
(Activity verified by 33PanQinaseTM-Assay)

Product Number 0332-0000-1
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