DMPK Kinase Activity Assay Service

Activity-based DMPK kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

DMPK

Enzyme

Human DMPK, wt

HGNC

DMPK

Manning ID

DMPK1

Synonym

DM, DM1, DM1PK, DMK, DMPK1, DMPK

UniProt

Q09013 (DMPK_HUMAN)

Kinase Type

Protein kinase

Kinase Group

AGC

Assay Properties

Assay Format

33PanQinaseTM

Substrates

bio-4xCHKT, ATP

Reaction

bio-4xCHKT + 33P-ATP = 33P-bio-4xCHKT + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 37
Sorafenib 10000
Sunitinb 100000

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice DMPK
345 wt Profiler Yes
345 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

No

Product Number N/A
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