DRAK1/STK17A Kinase Assay Service

Activity-based DRAK1/STK17A kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
DRAK1
Enzyme
Human DRAK1
HGNC
STK17A
Synonym
DRAK1
Substrates
Peptide substrate, [KKLNRTLSFAEPG], 20 µM
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Staurosporine17
Ro 31-82205,000
GW 50741,400
Scientific Information
Q9UEE5 (http://www.uniprot.org/uniprot/Q9UEE5)
Screening Location
Malvern, USA
Reference compound IC50 for DRAK1/STK17A
Reference compound IC50 for DRAK1/STK17A