DRAK2/STK17B Kinase Assay Service

Activity-based DRAK2/STK17B kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
DRAK2/STK17B
Enzyme
Human DRAK2/STK17B
HGNC
STK17B
Synonym
DAP kinase-related apoptosis-inducing protein kinase 2, Serine/threonine-protein kinase 17B
Scientific Information
O94768 (http://www.uniprot.org/uniprot/O94768)
Assay Properties
Substrates
Peptide substrate, [KKRPQRATSN-VFAM-NH2], 100 µM
ATP, 10 µM
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
Compounds IC50 (nM)
DRAK2-IN-1 (CAS No. 871837-60-4) 13.5
Staurosporine 8.5
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Biochemical Kinase Assays.
Reference compound inhibition of DRAK2/STK17B
Reference compound inhibition of DRAK2/STK17B
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