DYRK3 Kinase Activity Assay Service

Activity-based DYRK3 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

DYRK3

Enzyme

Human DYRK3, wt

HGNC

DYRK3

Manning ID

DYRK3

Synonym

DYRK5,  RED, REDK, RED, DYRK3

UniProt

O43781 (DYRK3_HUMAN)

Kinase Type

Protein kinase

Kinase Group

CMGC

Assay Properties

Assay Format

33PanQinaseTM

Substrates

RBER-IRStide, ATP

Reaction

RBER-IRStide + 33P-ATP = 33P-RBER-IRStide + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 290
Sorafenib 10000
Sunitinb 5000

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice DYRK3
345 wt Profiler Yes
345 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

No

Product Number N/A
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