EED Reader Domain Assay Service

EED Reader Domain Assay for compound screening and profiling using the HTRF assay format to measure compound binding to the target.
Target Overview
CAT#

EED-GST HTRF

Enzyme

Human Polycomb protein EED aa 2-441, GST-tagged

Synonyms

EED-GST/ b-H3K27Me3

Substrates

Biotinylated histone H3 peptide (21-44), K27Me3 (b-H3K27Me3)

Assay Properties
Reaction

HTRF binding assay

Readout

Fluorescence

Reference Compound IC50s

Compounds IC50 (nM)EED226 18A395 1.3

Scientific Information

O75530 (http://www.uniprot.org/uniprot/O75530)

Screening Location

Malvern, USA

Further information

More information can be found on our website Reader Domain Assay Services.

Reference Compound IC50 for EED-GST

Reference Compound IC50 for EED-GST