EIF2AK3 Kinase Activity Assay Service

Activity-based EIF2AK3 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

EIF2AK3

Enzyme

Human EIF2AK3, wt

HGNC

EIF2AK3

Manning ID

PEK

Synonym

DKFZp781H1925, PEK, PERK, WRS, EIF2AK3

UniProt

Q9NZJ5 (E2AK3_HUMAN)

Kinase Type

Protein kinase

Kinase Group

Other

Assay Properties

Assay Format

33PanQinaseTM

Substrates

Casein, ATP

Reaction

Casein + 33P-ATP = 33P-Casein + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Sorafenib 3000
Sunitinb 36000

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice EIF2AK3
345 wt Profiler Yes
345 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

No

Product Number N/A
Web Shop Reaction Biology Online Shop