Elastase Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Elastase
Enzyme
Human Neutrophil Elastase
Synonym
Bone marrow serine protease, Elastase-2, Human leukocyte elastase, Medullasin ELANE, ELA2
Substrates
Fluorogenic peptide [MeOSuc-AAPV-AMC], 10 µM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
| Sivelestat | 4.6 |
Scientific Information
P08246 (http://www.uniprot.org/uniprot/P08246)
Screening Location
Malvern, USA
Reference compound IC50 for Elastase
PDF