EPHA2 Kinase Activity Assay Service

Activity-based EPHA2 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

EPHA2

Enzyme

Human EPHA2, wt

HGNC

EPHA2

Manning ID

EphA2

Synonym

ECK, EPHA2

UniProt

P29317 (EPHA2_HUMAN)

Kinase Type

Protein kinase

Kinase Group

TK

Assay Properties

Assay Format

33PanQinaseTM

Substrates

PolyEY, ATP

Reaction

PolyEY + 33P-ATP = 33P-PolyEY + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 1133
Sorafenib 1600
Sunitinb 11000

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice EPHA2
345 wt Profiler Yes
345 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

Yes; ProQinaseTM – EPHA2
(Activity verified by 33PanQinaseTM-Assay)

Product Number 0368-0000-1
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