EPHA3 Kinase Activity Assay Service

Activity-based EPHA3 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

EPHA3

Enzyme

Human EPHA3, wt

HGNC

EPHA3

Manning ID

EphA3

Synonym

ETK, ETK1, EphA3, HEKECK, HEK4, TYRO4, EPHA3

UniProt

P29320 (EPHA3_HUMAN)

Kinase Type

Protein kinase

Kinase Group

TK

Assay Properties

Assay Format

33PanQinaseTM

Substrates

PolyEY, ATP

Reaction

PolyEY + 33P-ATP = 33P-PolyEY + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 87
Sorafenib 3200
Sunitinb 7700

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice EPHA3
345 wt Profiler Yes
345 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

Yes; ProQinaseTM – EPHA3
(Activity verified by 33PanQinaseTM-Assay)

Product Number 0351-0000-1
Web Shop Reaction Biology Online Shop