EPHA8 Kinase Activity Assay Service

Activity-based EPHA8 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

EPHA8

Enzyme

Human EPHA8, wt

HGNC

EPHA8

Manning ID

EphA8

Synonym

EEK, EphA8, HEK3, KIAA1459, EPHA8

UniProt

P29322 (EPHA8_HUMAN)

Kinase Type

Protein kinase

Kinase Group

TK

Assay Properties

Assay Format

33PanQinaseTM

Substrates

PolyEY, ATP

Reaction

PolyEY + 33P-ATP = 33P-PolyEY + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 1367
Sorafenib 10000
Sunitinb 62000

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice EPHA8
345 wt Profiler Yes
345 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

No

Product Number N/A
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