ERBB2 775YVMA776 Kinase Activity Assay Service

Activity-based ERBB2 775YVMA776 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

ERBB2 775YVMA776

Enzyme

Human ERBB2 775YVMA776, mutant

HGNC

ERBB2 (775YVMA776)

Manning ID

HER2/ErbB2

Synonym

ERBB2, CD340, HER2, MLN19, NGL, TKR1, ERBB2 775YVMA776

UniProt

P04626 (ERBB2_HUMAN)

Kinase Type

Protein kinase

Kinase Group

TK

Assay Properties

Assay Format

33PanQinaseTM

Substrates

PolyEY, ATP

Reaction

PolyEY + 33P-ATP = 33P-PolyEY + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 825
Sorafenib 10000
Sunitinb 71000

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice ERBB2 775YVMA776
345 wt Profiler No
345 IC50 wt Profiler No
Mutant Profiler Addon Yes
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

Yes; ProQinaseTM – ERBB2 775YVMA776
(Activity verified by 33PanQinaseTM-Assay)

Product Number 1525-0000-1
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