FAP Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
FAP
Enzyme
Human FAP
Synonym
Fibroblast activation protein alpha, 170 kDa melanoma membrane-bound gelatinase, Prolyl endopeptidase FAP, Gelatine degradation protease FAP
Assay Properties
Substrates
H-GP-AMC, 50 µM
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Talabostat mesylate | 467 |
Scientific Information
Q12884 (https://www.uniprot.org/uniprotkb/Q12884/entry)
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Protease Assay Services
Reference compound inhibition of FAP
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