FYN Y531F Kinase Activity Assay Service

Activity-based FYN Y531F kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

FYN Y531F

Enzyme

Human FYN Y531F, mutant

HGNC

FYN (Y531F)

Manning ID

FYN

Synonym

FYN, SLK, SYN, p59-FYN, cFYN, p59-Fyn, FYN Y531F, FYN (Y531F)

UniProt

P06241 (FYN_HUMAN)

Kinase Type

Protein kinase

Kinase Group

TK

Assay Properties

Assay Format

33PanQinaseTM

Substrates

PolyEY, ATP

Reaction

PolyEY + 33P-ATP = 33P-PolyEY + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 50
Sorafenib 10000
Sunitinb 530

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice FYN Y531F
345 wt Profiler No
345 IC50 wt Profiler No
Mutant Profiler Addon Yes
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

Yes; ProQinaseTM – FYN Y531F
(Activity verified by 33PanQinaseTM-Assay)

Product Number 1457-0000-1
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