GRK5 Kinase Assay Service

Activity-based GRK5 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
GRK5
Enzyme
Human GRK5
HGNC
GRK5
Synonym
GPRK5
Substrates
Casein, 1 mg/ml
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Staurosporine71
Ro 31-8220480
H-8953,000
Scientific Information
P34947 (http://www.uniprot.org/uniprot/P34947)
Screening Location
Malvern, USA
Reference compound IC50 for GRK5
Reference compound IC50 for GRK5