Hepsin Protease Assay Service

Hepsin Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.

Target Overview

CAT#

Hepsin

Enzyme

Human Serine Protease Hepsin

Synonym

Transmembrane protease serine 1, TMPRSS1, HPN

Substrates

Fluorogenic substrate Boc-QRR-AMC, 10 µM

Assay Properties

Readout

Enzymatic activity

Reference Compound IC50s
Compounds IC50 (nM)
Camostat Mesylate 5.57
Gabexate Mesylate 87.25
Leupeptin 82.99

Scientific Information

P05981 (http://www.uniprot.org/uniprot/P05981)

Screening Location

Malvern, USA

Reference compound IC50 for Hepsin