HIPK1 Kinase Activity Assay Service

Activity-based HIPK1 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

HIPK1

Enzyme

Human HIPK1, wt

HGNC

HIPK1

Manning ID

HIPK1

Synonym

KIAA0630, MGC26642, MGC33446, MGC33548, Myak, Nbak2, HIPK1

UniProt

Q86Z02 (HIPK1_HUMAN)

Kinase Type

Protein kinase

Kinase Group

CMGC

Assay Properties

Assay Format

33PanQinaseTM

Substrates

RBER-CHKtide, ATP

Reaction

RBER-CHKtide + 33P-ATP = 33P-RBER-CHKtide + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Sorafenib 10000
Sunitinb 4600

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice HIPK1
345 wt Profiler Yes
345 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

No

Product Number N/A
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