HIPK4 Kinase Assay Service

Activity-based HIPK4 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview

CAT#
HIPK4

Enzyme
Human HIPK4

HGNC
HIPK4

Synonym
FLJ32818

Substrates
MBP (Myelin Basic Protein), 10 µM
ATP 10 µM

Assay Properties

Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP

Readout
Enzymatic activity

Reference Compound IC50s
Compounds IC50 (nM)
Staurosporine 621
Ro 31-8220 961
GW 5074 882
Rottlerin 61,400
Scientific Information
Q8NE63 (http://www.uniprot.org/uniprot/Q8NE63)

Screening Location
Malvern, USA

Reference compound IC50 for HIPK4
Reference compound IC50 for HIPK4