HSP90a Heat Shock Protein Assay for compound screening and profiling via fluorescence polarization-based quantification of enzyme activity.
Target Overview
CAT#
HSP90a
Enzyme
Human HSP90a
Synonym
Heat shock protein HSP 90-alpha, Heat shock 86 kDa, HSP90AA1, HSP90A, HSPC1, HSPCA, HS90A
Substrate
Geldanamycin, 5 nM
Assay Properties
Readout
Binding competition with fluorescent geldanamycin
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Geldanamycin | 27.5 |
| Radicicol | 55.3 |
Scientific Information
P07900 (http://www.uniprot.org/uniprot/P07900)
Screening Location
Malvern, USA
Further information
More information can be found on our website Heat Shock Protein Assays.
Control Compound IC50 for HSP90a
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