IDH2 wt

Isocitrate dehydrogenase assay, Diaphorase/Resazurin-coupled assay
CAT#
IDH2 wt
Enzyme
Human IDH2 wild type
Synonym
Isocitrate dehydrogenase [NADP], mitochondrial (EC:1.1.1.42); ICD-M; Oxalosuccinate decarboxylase)
Substrate
150 µM isocitrate , 25 µM NADP
Reaction
isocitrate + NADP = a-KG + NADPH
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
IDH-C100227
Scientific Information
P48735 (http://www.uniprot.org/uniprot/P48735 )
Screening Location
Malvern, USA
Reference compound IC50 for IDH2 WT
Reference compound IC50 for IDH2 WT