IGF1R Kinase Assay Service

Activity-based IGF1R kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#
IGF1R
Enzyme
Human IGF1R
HGNC
IGF1R
Synonym
JTK13
Substrates
Peptide substrate, [KKKSPGEYVNIEFG], 20 µM
ATP 10 µM
Assay Properties
Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (nM)
Staurosporine9.0
PP2>20,000
Scientific Information
P08069 (http://www.uniprot.org/uniprot/P08069)
Screening Location
Malvern, USA
Reference compound IC50 for IGF1R
Reference compound IC50 for IGF1R