IRAK4 aa104-460 (untagged) Kinase Activity Assay Service

Activity-based IRAK4 aa104-460 (untagged) kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

IRAK4 aa104-460 (untagged)

Enzyme

Human IRAK4 aa104-460 (untagged), wt

HGNC

IRAK4 (aa104-460) untagged

Manning ID

IRAK4

Synonym

REN64, NY-REN-64, IRAK4, IRAK4 (untagged), IRAK4 aa104-460 (untagged)

UniProt

Q9NWZ3 (IRAK4_HUMAN)

Kinase Type

Protein kinase

Kinase Group

TKL

Assay Properties

Assay Format

33PanQinaseTM

Substrates

Histon H2B, ATP

Reaction

Histon H2B + 33P-ATP = 33P-Histon H2B + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 38
Sorafenib 10000
Sunitinb 33000

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice IRAK4 aa104-460 (untagged)
345 wt Profiler No
345 IC50 wt Profiler No
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

Yes; ProQinaseTM – IRAK4 aa104-460 (untagged)
(Activity verified by 33PanQinaseTM-Assay)

Product Number 0586-0000-1
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