JNK2 Kinase Activity Assay Service

Activity-based JNK2 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

JNK2

Enzyme

Human JNK2, wt

HGNC

MAPK9

Manning ID

JNK2

Synonym

JNK-55, JNK2A, JNK2ALPHA, JNK2B, JNK2BETA, PRKM9, p54aSAPK, MAPK9, JNK2-alpha2, SAPK, p54a, JNK-alpha2, JNK2

UniProt

P45984 (MK09_HUMAN)

Kinase Type

Protein kinase

Kinase Group

CMGC

Assay Properties

Assay Format

33PanQinaseTM

Substrates

ATF2, ATP

Reaction

ATF2 + 33P-ATP = 33P-ATF2 + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 2533
Sorafenib 3400
Sunitinb 73000

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice JNK2
345 wt Profiler Yes
345 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

Yes; ProQinaseTM – JNK2
(Activity verified by 33PanQinaseTM-Assay)

Product Number 0459-0000-1
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