L3MBTL1-His MBT Reader Domain Assay for compound screening and profiling using the AlphaScreen® assay format to measure compound binding to the target.
Target Overview
CAT#
L3MBTL1-His
Enzyme
Human L3MBTL1-His
Synonyms
Lethal(3)malignant brain tumor-like protein 1, H-l(3) mbt, L(3) mbt-like, L(3)mbt protein homolog, KIAA0681, L3MBT, L3MBTL
Scientific Information
Q9Y468 (https://www.uniprot.org/uniprotkb/Q9Y468)
Assay Properties
Substrates
Histone H3 peptide (1-21) K4-Me1-Biotin
Reaction
AlphaScreen® Binding assay
Readout
Fluorescence
Reference Compound IC50s
| Compounds | IC50 (µM) |
|---|---|
| UNC1215 | 4.6 |
| UNC669 | 9.5 |
Screening Location
Malvern, PA, USA
Further information
More information can be found on our website Reader Domain Assay Services.
Reference Compound IC50 for L3MBTL1-His
PDF