L3MBTL3-His MBT Bromodomain Assay Service (AlphaScreen)

L3MBTL3-His MBT Reader Domain Assay for compound screening and profiling using the AlphaScreen® assay format to measure compound binding to the target.

Target Overview

CAT#

L3MBTL3-His

Enzyme

Human L3MBTL3-His

Synonyms

Lethal(3)malignant brain tumor-like protein 3, H-l(3), mbt-like protein 3, L(3)mbt-like protein 3, L3mbt-like 3, MBT-1, KIAA1798, MBT1

Scientific Information

Q96JM7 (https://www.uniprot.org/uniprot/Q96JM7)

Assay Properties

Substrates

Histone H4 peptide (8-30) K20-Me2-Biotin

Reaction

AlphaScreen® Binding assay

Readout

Fluorescence

Reference Compound IC50s
Compounds IC50 (µM)
UNC1215 0.015
UNC669 11.92

Screening Location

Malvern, PA, USA

Further information

More information can be found on our website Reader Domain Assay Services.

Reference Compound IC50 for L3MBTL3-His

Reference Compound IC50 for L3MBTL3-His