Activity-based LATS2 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology
Target Overview
RBE Target ID
LATS2
Enzyme
Human LATS2, wt
HGNC
LATS2
Manning ID
LATS2
Synonym
FLJ13161, LATS
UniProt
Q9NRM7 (LATS2_HUMAN)
Kinase Type
Protein kinase
Kinase Group
AGC
Assay Properties
Assay Format
33PanQinaseTM
Substrates
MBP, ATP
Reaction
MBP + 33P-ATP = 33P-MBP + ADP
Readout
Enzymatic activity
Technical Reference Compound IC50 value(s)
| Compounds | IC50 (nM) |
|---|---|
| Staurosporine | 3.5 |
| Sorafenib | 11000 |
| Sunitinib | 1200 |
Screening Location
Freiburg, Germany
Further Information
More information can be found on our website Kinase Assays
Service and Product Availability
Screening Opportunities
| FreeChoice | LATS2 |
| wt Profiler Panel | No |
| IC50 wt Profiler Panel | No |
| Mutant Profiler Addon | No |
| Lipid Kinase Profiler Addon | No |
| IC50 Profiler | No |
Recombinant Protein Availability
| Active recombinant protein | No |
| Product Number | N/A |
| Web Shop | Reaction Biology Online Shop |
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