LYNB Kinase Assay Service

Activity-based LYNB kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview
CAT#

LYN B

Enzyme

Human LYN B

HGNC

LYN (d23-43)

Synonym

JTK8

Substrates

Peptide substrate, poly[Glu:Tyr] (4:1), 0.2 mg/ml
ATP 10 µM

Assay Properties
Reaction

Substrate + [γ-33P]-ATP = 33P-Substrate + ADP

Readout

Enzymatic activity

Reference Compound IC50s
Compounds IC50 (nM)
Staurosporine 4.5
PP2 520
AG1478 1,900
D-64406 3,300
Scientific Information

P07948-2 (http://www.uniprot.org/uniprot/P07948-2)

Screening Location

Malvern, USA

Further information

More information can be found on our website Kinase Assays.

Reference compound IC50 for LYNB

Reference compound IC50 for LYNB