MALT1 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
MALT1
Enzyme
Human MALT1
Synonym
MALT lymphoma-associated translocation, Paracaspase, MLT
Scientific Information
Q9UDY8 (http://www.uniprot.org/uniprot/Q9UDY8)
Assay Properties
Substrate
Ac-LRSR-MCA, 25 µM
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 |
|---|---|
| MALT1 inhibitor MI-2 | 1.58 µM |
| MLT-747 | 22 nM |
| Safimaltib | 6.81 nM |
Screening Location
Malvern, PA, USA
Further Information
More information can be found on our website Protease Assays.
Reference compound inhibition of MALT1
PDF