MAP4K5 Kinase Activity Assay Service

Activity-based MAP4K5 kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

MAP4K5

Enzyme

Human MAP4K5, wt

HGNC

MAP4K5

Manning ID

KHS1

Synonym

GCKR, KHS, MAPKKKK5, KHS1, MAP4K5, KHS/MAP4K5

UniProt

Q9Y4K4 (M4K5_HUMAN)

Kinase Type

Protein kinase

Kinase Group

STE

Assay Properties

Assay Format

33PanQinaseTM

Substrates

Casein, ATP

Reaction

Casein + 33P-ATP = 33P-Casein + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 2
Sorafenib 510
Sunitinb 43

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice MAP4K5
345 wt Profiler Yes
345 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

No

Product Number N/A
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