MAPKAPK3 Kinase Assay Service

Activity-based MAPKAPK3 kinase assay for compound screening and profiling via radiometric HotSpotTM kinase assay.
Target Overview

CAT#
MAPKAPK3

Enzyme
Human MAPKAPK3

HGNC
MAPKAPK3

Synonym
3PK, MAPKAP, MAPKAP3

Substrates
Peptide substrate, [KKLNRTLSVA], 20 µM
ATP 10 µM

Assay Properties

Reaction
Substrate + [γ-33P]-ATP = 33P-Substrate + ADP

Readout
Enzymatic activity

Reference Compound IC50s
Compounds IC50 (nM)
Staurosporine 4,000
GW 5074 6,400
Scientific Information
Q16644 (http://www.uniprot.org/uniprot/Q16644)

Screening Location
Malvern, USA

Reference compound IC50 for MAPKAPK3
Reference compound IC50 for MAPKAPK3

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