MASTL Kinase Activity Assay Service

Activity-based MASTL kinase assay for compound screening and profiling via 33PanQinaseTM – assay technology

Target Overview

RBE Target ID

MASTL

Enzyme

Human MASTL, wt

HGNC

MASTL

Manning ID

MASTL

Synonym

FLJ14813,  RP11-85G18.2, THC2, MASTL, GLW, GREATWALL, GWL, hGWL, MAST-L

UniProt

Q96GX5 (GWL_HUMAN)

Kinase Type

Protein kinase

Kinase Group

AGC

Assay Properties

Assay Format

33PanQinaseTM

Substrates

RBER-NTRK3tide, ATP

Reaction

RBER-NTRK3tide + 33P-ATP = 33P-RBER-NTRK3tide + ADP

Readout

Enzymatic activity

Technical Reference Compound IC50 value(s)
Compounds IC50 (nM)
Staurosporine 1000
Sorafenib 10000
Sunitinb 9200

Screening Location

Freiburg, Germany

Further Information

More information can be found on our website Kinase Assays

Service and Product Availability

Screening Opportunities
FreeChoice MASTL
345 wt Profiler Yes
345 IC50 wt Profiler Yes
Mutant Profiler Addon No
Lipid Kinase Profiler Addon No
IC50 Profiler No
Recombinant Protein Availability
Active recombinant protein

Yes; ProQinaseTM – MASTL
(Activity verified by 33PanQinaseTM-Assay)

Product Number

1593-0000-2

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