Matriptase 2 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
Matriptase 2
Enzyme
Human Matriptase 2
Synonym
Transmembrane protease serine 6, TMPRSS6
Substrates
Fluorogenic peptide [Boc-QAR-AMC], 10 µM
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (µM) |
|---|---|
| Gabexate mesylate | 0.42 |
Scientific Information
Q8IU80 (http://www.uniprot.org/uniprot/Q8IU80)
Screening Location
Malvern, USA
Reference compound IC50 for Matriptase 2
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