mHDAC6 Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
mHDAC6
Enzyme
Mouse HDAC6
Synonyms
Protein deacetylase HDAC6, Tubulin-lysine deacetylase HDAC6, mHDA2
Assay Properties
Substrates
Fluorogenic peptide from p53 residues 379-382 (RHKKAc), 10 μM
Readout
Enzymatic activity
Reference Compound IC50s
| Compounds | IC50 (nM) |
|---|---|
| Trichostatin A | 0.6 |
Scientific Information
Q9Z2V5 (http://www.uniprot.org/uniprot/Q9Z2V5)
Screening Location
Malvern, PA, USA
Further information
More information can be found on our website HDAC Assay (Histone Deacetylase Assay) and Sirtuin Assay Services.
Reference Compound IC50 for mouse HDAC6
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