MMP 13 Protease Assay Service

MMP 13 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
MMP13
Enzyme
MMP-13, catalytic domain from human recombinant (residues 85-255) expressed in E. coli with C-terminal tag
Synonym
Matrix metalloproteinase-13, MMP-13
Substrates
(5-FAM/QXLTM) FRET peptide
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (M)
NNGH2.57E-09
Actinonin2.16E-08
GM60011.13E-10
MMP Inhibitor III4.40E-10
MMP-9/MMP-13 Inhibitor I7.22E-10
Scientific Information
P45452 (http://www.uniprot.org/uniprot/P45452)
Screening Location
Malvern, USA
Reference compound IC50 for MMP-13
Reference compound IC50 for MMP-13