MMP 1 Protease Assay Service

MMP 1 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
MMP1
Enzyme
MMP-1, catalytic domain from human recombinant (residues 81-249) expressed in E. coli with C-terminal tag
Synonym
Matrix metalloproteinase-1, Fibroblast Collagenase
Substrates
(5-FAM/QXLTM) FRET peptide
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (M)
NNGH7.51E-08
Actinonin5.19E-08
GM60015.19E-10
MMP Inhibitor III2.10E-10
MMP-9/MMP-13 Inhibitor I4.75E-08
Scientific Information
P03956 (http://www.uniprot.org/uniprot/P03956)
Screening Location
Malvern, USA
Reference compound IC50 for MMP-1
Reference compound IC50 for MMP-1