MMP 3 Protease Assay Service

MMP 3 Protease Assay for compound screening and profiling via fluorescence-based quantification of enzyme activity.
Target Overview
CAT#
MMP3
Enzyme
MMP-3, catalytic domain from human recombinant (residues 83-255) in E. coli with C-terminal tag
Synonym
Matrix metalloproteinase-3, MMP-3, Transin-1, SL-1
Substrates
(5-FAM/QXLTM) FRET peptide
Assay Properties
Readout
Enzymatic activity
Reference Compound IC50s
CompoundsIC50 (M)
NNGH1.65E-08
Actinonin7.23E-07
GM60011.80E-8
MMP-9/MMP-13 Inhibitor I1.41E-08
MMP-2/MMP-3 Inhibitor I5.16E-06
Scientific Information
P08254 (http://www.uniprot.org/uniprot/P08254)
Screening Location
Malvern, USA
Reference compound IC50 for MMP-3
Reference compound IC50 for MMP-3